Suping Yu

Visiting Student, 2017-2018

Ph.D. candidate, Tsinghua University, China

B.S. Ocean University of China, China, 2013

ysp13@mail.tsinghua.edu.cn

I’m a visiting student in Dr. Qilin Li’s lab, working on membrane biofouling control with environment-friendly methods.

The biofilm is a life form caused by adhering and aggregating of bacteria on solid surface or liquid-air interface and is found responsible for membrane biofouling. In the previous study, D-tyrosine was reported to prevent biofilm formation of Pseudomonas aeruginosa PAO1, a common type of bacteria which is easy to form biofilm, at an effective concentration of 5 nM. However, it was unclear that wether this biochemical signal compounds interfere equally effectively towards antibiotic bacteria.

My goal is, firstly, to study the properties of biofilm formed by antibiotic PAO1; secondly, to study the effect of D-tyrosine on biofilm inhibition at different concentrations; thirdly, to investigate whether the mechanisms of biofilm inhibition are different between PAO1 and antibiotic PAO1.